皮肤和毛发异常小鼠突变手册：动物模型和生物医学工具

English | 1994 | pages: 559 | ISBN: 0849383722 | PDF | 58,3 mb

Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.

英文| 1994 |页数：559 |国际标准图书编号：0849383722 | PDF | 58,3 mb 《皮肤和毛发异常小鼠突变手册》介绍了48种小鼠突变，这些突变都可供生物医学界使用。对许多患有皮肤病的小鼠突变进行了详细的回顾和说明。这本流行的参考书为您提供了一个单一的来源，用于确定哪种小鼠突变最能满足您的需求，作为复杂研究项目的生物医学工具。本书还概述了家畜遗传性皮肤病，以提供不存在的小鼠模型的替代品或补充现有的小鼠模型。著名专家撰写的详细章节比较了人类和小鼠皮肤和皮肤病的生物学，包括动物模型的开发和使用、哺乳动物遗传学、角蛋白生物化学、表皮和毛囊周期和动力学、细胞因子和生长因子、角质形成细胞培养系统、皮肤癌变、皮肤免疫系统以及与内分泌系统突变相关的皮肤变化。

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