神经系统疾病的基因疗法：针对靶向治疗的分子方法

English | 2024 | ISBN: 9781003494102 | 238 pages | True PDF | 28.44 MB

Neurological illnesses pose one of the biggest hazards to the healthcare system today. This new book brings together the latest methods of gene therapy that can be used to treat both inherited and sporadic neurodegenerative diseases. It presents the most significant advances in gene transfer methods as well as the most recent understandings of the mechanisms behind specific neurodegenerative illnesses, placing these into the context of gene therapy approaches for the central nervous system. The book introduces the basics of neurodegenerative conditions and the physiological basis for their occurrence in humans. It also discusses the various proteins useful in neuro diseases and their viral applications. The book explores how stem cells can be used to learn about the future of gene therapy along with the significance of the sequences that silence genes. It discusses the functions of astrocytes in different brain regions, as well as in-vivo research in gene therapy for neurodegenerative disorders.

神经系统疾病目前是医疗系统面临的最大风险之一。这本新书将最新的基因疗法方法汇集起来，这些方法可用于治疗遗传性和散发性神经退行性疾病。它展示了最显著的基因转移方法进展以及对特定神经退行性疾病机制的最新理解，并将其置于针对中枢神经系统的一系列基因疗法策略框架内。这本书介绍了神经系统疾病的基本情况及其在人类中发生的生理基础。此外，还讨论了神经疾病中使用的各种蛋白质及其病毒应用。该书探讨了如何利用干细胞了解基因治疗的未来以及沉默基因序列的重要性。它还讨论了不同脑区中的星形胶质细胞的功能，以及针对神经退行性疾病的在体内基因疗法研究。

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