microRNAs,人类健康与疾病
This new volume of the book series Epigenetics and Human Health is dedicated to microRNAs (miRNAS), regulatory non-coding RNAs that have important roles in the control of gene expression both at posttranscriptional and transcriptional levels.
Endogenous miRNAs regulate gene expression patterns in a sequence-specific manner. These short sequences may serve as potential therapeutic targets in the treatment of complex diseases including cancer, cardiovascular diseases, neurocognitive disorders, respiratory diseases and pathogenic infections. Moreover, miRNAs hold promise to be used as extensive diagnostic and prognostic markers of disease.
miRNAs, Human Health and Disease is an essential reading for graduate and undergraduate students, researchers, and academics interested in the latest developments on non-coding RNA-mediated pathways associated with health and disease.
《表观遗传学与人类健康》新卷 dedicated 给microRNAs(miRNA),一种在转录后和转录水平上控制基因表达具有重要角色的非编码RNA。 微小RNA通过特定序列调节基因表达模式。这些短序列可能作为治疗复杂疾病,包括癌症、心血管疾病、神经认知障碍、呼吸系统疾病及病原体感染等疾病的潜在靶标。此外,miRNAs有潜力成为疾病诊断和预后标记物的广泛使用者。 《miRNAs, Human Health and Disease》是研究生、本科生学生以及对与健康和疾病相关的非编码RNA介导途径最新发展感兴趣的科研人员和学者们不可或缺的阅读材料。
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