辅助生殖中的冷冻保存：一个从业者的治疗方法、管理和组织指南
Cryopreservation of oocytes, sperm, and ovarian and testicular tissues, as well as embryos, is one of the most critical procedures to preserve the reproductive capacity of individuals. It is an indispensable part of assisted reproductive technologies, as nearly all IVF clinics around the world have embraced the freeze-all embryo strategy with no fresh embryo transfers. Advanced platforms, such as automation and artificial intelligence, are making their way into all aspects of assisted reproductive technologies, including reproductive tissue banking process and storage. At the same time, lax regulations and lack of training combined with rapid demands of IVF services have resulted in a climate of frequent disaster and catastrophic incidents from the cryo labs that store thousands of patients’ embryos for years. With the onset of malpractice lawsuits against the clinics and awards of large compensation to the patients, regulations are getting stricter in this arena to safeguard the integrity of storage systems, and industry leaders are developing advanced devices and alarm systems to remotely monitor storage systems exploring the power of internet, AI and automation. Therefore, there is an urgent need for a comprehensive text in this field based on the introduction of such a wide array of advanced devices, newer technologies, regulatory frameworks, risks and disaster management options.
卵子、精子、卵巢和睾丸组织以及胚胎的冷冻保存是保存个人生殖能力的关键步骤之一。它是辅助生育技术中不可或缺的一部分，因为全球几乎所有的人工授精诊所都采用了“冻存所有胚胎”的策略，不再进行新鲜胚胎移植。先进的平台如自动化技术和人工智能正在进入辅助生育技术的所有方面，包括生殖组织银行过程和存储。与此同时，宽松的监管和缺乏培训，加上对人工授精服务需求的迅速增加，导致了频繁发生灾难性事件和严重事故，这些事件发生在存储成千上万患者胚胎的冷冻实验室中。随着针对诊所提起的医疗过失诉讼以及向患者支付巨额赔偿金的情况出现，该领域在这一领域的监管越来越严格，以保护储存系统的完整性，并且行业领导者正在开发先进的设备和报警系统来远程监控储存系统，探索互联网、人工智能和自动化的力量。因此，在这样广泛引入了许多先进设备、新科技、法规框架、风险管理和灾难应对选项的基础上，迫切需要针对这个领域的全面指南。
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