《脑卒中遗传学(第三版)》
This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.
此次修订后的、扩展的第三版不仅更新了读者对这一快速发展的领域的了解,还通过使用中风作为范例来提供复杂疾病遗传学的整体理解。读者将获得关于脑血管遗传学的全面理解,包括缺血性和出血性中风的遗传基础的流行病学证据、其分子基础的知识(从关联、链接到最近的全基因组研究),以及单基因障碍的知识。最后,讨论了处理这些问题时所涉及的法律和伦理复杂性。
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