MR-Linac的实际操作指南：技术创新与临床意义

English | PDF EPUB (True) | 2024 | 484 Pages | ISBN : 303148164X | 143 MB

This book offers a detailed guide to MR-Linac, a unique and fast growing radiation treatment modality. MR-linac is new technology that is a fusion of an MRI and a linear accelerator on the same gantry. It can change both target volume delineation and tumor visualization in real time using MR-cine images and treatment. Tumor location changes moment to moment as radiation is delivered, but this cannot be visualized in current radiation therapy practices. This new and rapidly growing technology can provide adaptive therapy that was not possible before. This book presents current knowledge on MR-linac technology, clinical practices, and ultimately patient outcome where dose escalation is not possible due to limiting normal tissue structures in the vicinity of tumor. There are two commercial MR-linac machines under consideration and both will be covered in detail. The book is divided into four sections. The first gives a general introduction to MR-Linac, covering the role of MRI inradiation oncology, the clinical necessity of this technology, and patient selection. The next section details the physics and technology of MR-Linac, covering image sequence, motion management, and treatment planning. Section three offers the clinical applications of MR-Linac and is divided by body area, including lung, prostate, and breast. Finally, the fourth section looks to the future and what this technology can mean for radiation oncology. This is an ideal guide for radiation oncologists, medical physicists, and relevant trainees.

这本书提供了一份详细的MR-Linac指南，这是一种独特的且快速发展的放疗模式。MR-Linac是一种将MRI和直线加速器结合在同一治疗机架上的新技术。它可以实时使用MR-cine图像来定义靶体积并可视化肿瘤，并在放射治疗过程中随时间变化。肿瘤位置会随辐射传递而不断变化，但在当前的放射治疗方法中无法进行视觉化。这种新的快速发展的技术可以提供之前不可实现的自适应疗法。 本书介绍了关于MR-Linac技术、临床实践以及最终患者的结局知识，这些结局受限于肿瘤附近正常组织结构不允许剂量递增。目前考虑了两种商用MR-Linac机器，并且都将详尽介绍。这本书分为四个部分。第一部分介绍了MR-Linac的总体情况，涵盖了MRI在放射肿瘤学中的作用、这种技术的临床必要性以及患者的选择。接下来的部分详细介绍了MR-Linac的技术和物理学，包括图像序列、运动管理以及治疗规划的内容。第三部分则探讨了MR-Linac的临床应用，并按身体部位划分（包括肺部、前列腺和乳腺）。最后，第四部分展望了未来，讨论了这种技术对放射肿瘤学可能产生的影响。 这本书适合放疗医生、医学物理学家及相关学生作为理想的参考指南。

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