《临床免疫学:原理与实践》第六版
Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes complete coverage of common and uncommon immunologic disorders. Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume.
Includes extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine. Contains new chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma. Provides new genetics content focused on data applications. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. Summarizes promising research and development anticipated over the next 5–10 years with "On the Horizon" boxes and discussions of translational research. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
提供全面覆盖基本科学和临床场景的独特的临床免疫学:原理与实践,第6版带您了解这一快速变化领域的各个方面。它考察了免疫性疾病及其系统性影响的分子、细胞和免疫学基础;同时也包含了常见和罕见免疫性疾病完整的覆盖范围。该书更新至最新的免疫学研究和临床影响,包括突破性的免疫疗法以及基于分子的治疗方案,该全面修订版提供了一些最杰出全球免疫学领导者的权威指导,整合在一个完整且插图丰富的卷中。 包含广泛的修订,反映了迅速扩大的研究和临床进展,包括免疫检查点抑制剂、癌症免疫疗法、精准医学和输血医学等突破性药物与免疫疗法。 包含了关于COVID-19、免疫反应和免疫系统作用的新章节;免疫调节缺陷;免疫检查点;CAR T细胞,包含新的基于细胞的免疫疗法;基因治疗,包括CRISPR和基因选择;以及一个以临床为重点的哮喘章节。 专注于数据应用提供新内容,聚焦于遗传学。 涵盖重点领域的重要进展,例如微生物群在正常免疫系统发育和免疫性疾病发病机制中的作用的重要性;先天性和适应性免疫系统的相互关系;快速且成本效益好的基因组学进步;细胞信号路径和细胞表面分子结构;等等。 涵盖了热点话题,包括遗传学与基因组学在免疫反应和免疫性疾病、动脉粥样硬化、复发性发热综合症、衰老以及固有免疫缺陷中的角色;微生物群在正常免疫系统发育和免疫疾病发病机制中的作用;新型疗法的潜力。 提供一个用户友好的格式,通过带有关键信息高亮的彩色框来突出关键概念、临床珍珠、临床相关性和治疗原则。 总结了未来5-10年内期待的研究和发展情况,“On the Horizon”章节以及对转化研究的讨论。 随购附赠电子书版本。电子书允许您访问所有文字、图表和参考文献,具有搜索、自定义内容、做笔记和高亮显示功能,以及可以朗读内容的功能。
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