靶向炎症性肺疾病中的表观遗传学
This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.
这本书讨论了表观遗传学在不同肺部疾病发病机制中的作用,包括慢性阻塞性肺病、肺癌、肺结核、特发性肺纤维化和肺部感染。它还探索了DNA和组蛋白的翻译后修饰以提高对肺部疾病的了解。这本书有助于理解表观遗传学机制并发展出新的诊断和治疗方法。此外,这本书提供了关于表观遗传调控炎症的分子机制的见解,这可能为设计针对表观遗传机器的小分子抑制剂提供新思路,这些小分子抑制剂可有效治疗各种与炎症相关的疾病。这本书对从事呼吸生物学领域的学者、研究人员和行业专业人士具有重要的价值资源。
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