环境压力源和氧化炎症组织反应

English | 2023 | ISBN: 9781003328100 | 302 pages | True PDF | 10.6 MB

Environmental risk factors – noise, air pollution, chemical agents, and ultraviolet radiation – impact human health by contributing to the onset and progression of noncommunicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensive summary of major findings. This book is a state-of-the-art summary of these myriad severe life stressors. The chapters on the different pollutants focus on disease mechanisms (cardiovascular, neurological and metabolic disorders) and on oxidative stress and inflammation. The editors emphasize emerging mechanisms based on dysregulation of the circadian clock, the microbiome, epigenetic pathways, and cognitive function by environmental stressors, and introduce the exposome concept while highlighting existing research gaps.

Key Features Links various environmental stressors to the incidence of noncommunicable diseases Includes chapters on airborne toxins, chemical pollutants, noise, and ultraviolet radiation stressors Contributions from an international team of leading researchers Summarizes the impacts of stressors on disease mechanisms

环境风险因素——噪音、空气污染、化学剂和紫外线辐射——通过促进非传染性疾病的发生和发展来影响人类健康。因此，需要进行临床前和临床研究，并对主要发现进行全面总结。这本书是对这些各种各样的生活压力的现代综合概述。各个章节关注不同的污染物疾病机制（心血管、神经系统和代谢紊乱）以及氧化应激和炎症。编辑们强调基于环境压力导致昼夜节律失调、微生物组、表观遗传途径及认知功能失常的新兴机制，并在突出现有研究空白的同时介绍暴露组学的概念。 关键特性 将各种环境压力因素与非传染性疾病的发生率联系起来 包含关于空气中有毒物质、化学污染物、噪音和紫外线辐射压力的章节 由国际顶尖研究人员贡献的文章 总结了压力对疾病机制的影响

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